Sant' Ambrogio vacation rentals
We found 2,673 vacation rentals — enter your dates for availability
Discover a selection of 210 apartments and other vacation rentals in Sant' Ambrogio that are perfect for your trip. Whether you're staying in a vacation rental with a group or just with your pet, you'll have the amenities you expect and more, which might include air conditioning and a pool. You'll be sure to find a rental for everyone's needs, including options that are accessible or non-smoking.
Holiday rentals with weekly discounts - Sant' Ambrogio
Showing deals for:Jan 15 - Jan 22

Exceptional
(35 reviews)
Apartment overlooking the Duomo
Florence
$203
$1,421 for 7 nights
All fees included

Exceptional
(16 reviews)
Steps to Ponte Vecchio.3BR/3BA+terrace w view of Pitti Palace
Florence
$486
$3,404 for 7 nights
All fees included

Exceptional
(52 reviews)
DANTE ROOF TERRACE HOUSE
Florence
$575
$4,023 for 7 nights
All fees included

Exceptional
(45 reviews)
APARTMENT WITH 2-BEDROOM IN THE HISTORIC CENTER + PRIVATE PARKING
Florence
$217
$1,521 for 7 nights
All fees included

Exceptional
(117 reviews)
BRIGHT LOFT IN THE HEART OF FLORENCE, JUST A FEW STEPS FROM THE UFFIZI
Florence
$154
$1,081 for 7 nights
All fees included

Exceptional
(64 reviews)
Spacious and charming apartment in the heart of Florence
Florence
$308
$2,155 for 7 nights
All fees included

Exceptional
(190 reviews)
Charming 3 bedroom Brand New Apartment in a Historic Building.
Florence
$350
$2,448 for 7 nights
All fees included

Exceptional
(19 reviews)
A Charming Gem in the Heart of Florence
Florence
$223
$1,559 for 7 nights
All fees included

Exceptional
(144 reviews)
Just a few minutes from the Cathedral and the most beautiful Monuments in town
Florence
$78
$549 for 7 nights
All fees included

Exceptional
(97 reviews)
Tuscan-style apartment facing Duomo
Florence
$260
$1,817 for 7 nights
All fees included

Exceptional
(153 reviews)
A Few Steps From Duomo Cathedral and SMN train station
Florence
$209
$1,466 for 7 nights
All fees included

Exceptional
(9 reviews)
David Sweet Suite
Florence
$175
$1,227 for 7 nights
All fees included

Exceptional
(60 reviews)
Located in the most chic area of Florence, trendy clubs near Ponte Vecchio
Florence
$262
$1,832 for 7 nights
All fees included

Exceptional
(9 reviews)
Ponte Vecchio, Art & Design in Historic Palace
Florence
$504
$3,527 for 7 nights
All fees included

Exceptional
(34 reviews)
CasaGiardinoUno Simply Florence
Florence
$299
$2,091 for 7 nights
All fees included

Exceptional
(9 reviews)
Charming Apartment in the shadow of Giotto's bell tower
Florence
$265
$1,853 for 7 nights
All fees included

Exceptional
(123 reviews)
YOUR "BEAUTIFUL" VIEW ON FLORENCE!
Florence
$211
$1,476 for 7 nights
All fees included

Exceptional
(45 reviews)
Palazzetto dei Nobili apartment
Florence
$254
$1,775 for 7 nights
All fees included

Exceptional
(15 reviews)
Apartment LaCosta near Ponte Vecchio
Florence
$174
$1,220 for 7 nights
All fees included

Exceptional
(133 reviews)
The emotion of living in a Renaissance palace in the heart of Florence
Florence
$310
$2,168 for 7 nights
All fees included

Exceptional
(150 reviews)
APPARTAMENT IN THE CITY CENTER OF FLORENCE
Florence
$145
$1,017 for 7 nights
All fees included
Find spaces that suit your style
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Find the best place to stay - Sant' Ambrogio

Modern Murate View in Florence by Mmega
Sleeps 6 · 2 bedrooms · 2 bathrooms

Fabulous 200sqm bright, new apartment walking distance to Duomo and city centre
Sleeps 12 · 5 bedrooms · 3 bathrooms

casaRIMA, elegant and bright apartment, Florence historical center
Sleeps 6 · 2 bedrooms · 2 bathrooms

Palazzo dei Ciompi Suites
Sleeps 3 · 1 bedroom

Bright and wide, wonderful apt in the center of the city
Sleeps 8 · 5 bedrooms · 3 bathrooms
Top rated rentals - Sant' Ambrogio

Best Luxury Property in Florence!
This property is under-rated and we are thankful we stumbled upon this. We had a nearly 3000 sf apartment to ourselves and the photos don't do it justice. We stay at luxury lodging everywhere we go and this was no different. There was so much room to relax and spread out. Great for multi family, or large family. Our unit on the second floor was ideal because the bedrooms were in the ack and very quiet. While the main living areas overlook this beautiful street with opera singers and live music in the afternoon. It radiates throughout the room. This place is gorgeous and worth every penny. Very clean and had everything you could need to stay for a lengthy period of time. Very centrally located too!
Richard
Stayed Oct 2025

Contemporary and Clean
This hotel was located in the heart of the city center and yet our room had no noise issues at all. We had access to all shopping, restaurants, museums and historical landmarks within just minutes of walking. The suite was a comfy one bedroom with kitchen, dishwasher, microwave, and washing machine. A couple of quick notes for international travelers, when you leave the room all power is turned off and also allow plenty of time for drying of laundry (since the units are lower power). Use the racks provided to complete drying.
Thu
Stayed Sep 2021

Palazzo Doni
Exceeded expectations
Emilio M
Stayed Jun 2025

Great hotel, steps from the Dome
Great hotel, ample, comfortable and cozy rooms. Friendly and professional staff. Safe area, within walking distance from everything (restaurants, bars, museums, shopping, churches, etc)
Vivi
Stayed Sep 2017

Great weekend in Florence
This apartment was perfect for our weekend in Florence. Had everything we needed and the space was larger than we expected. Very clean and a close walk to anything we wanted to visit. We had a car and the property manager was helpful giving us parking tips that were very close to the apartment. Would stay here again.
Glenn W.
Stayed Jun 2024

Awesome view, location and spacious
The property is as described and matches the pictures. It's spacious and the location is absolutely amazing. Step outside for a view of the Duomo. Alejandro is a great host and was very communicative and available. The apartment and linens were clean but would be even better if they didn't have stains.
Gabriel R.
Stayed Sep 2024
- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
How much does it cost to rent a vacation home in Sant' Ambrogio?
Prices for vacation rentals in Sant' Ambrogio vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Sant' Ambrogio to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Sant' Ambrogio vacation house rentals?
You can find great discounts on house rentals in Sant' Ambrogio on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Are there any Sant' Ambrogio vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Sant' Ambrogio with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I find long-stay vacation rentals in Sant' Ambrogio?
A long-stay vacation rental in Sant' Ambrogio is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
When is the best time to visit Sant' Ambrogio for a vacation rental?
The most popular time to visit Sant' Ambrogio is in September, when the summer heat begins to mellow and the vineyards are alive with the grape harvest. This month offers an ideal blend of warm temperatures, typically in the mid-70s to low 80s Fahrenheit, superb for exploring the picturesque Tuscan countryside and indulging in wine tastings at local wineries.The peak tourist season runs from July to September, attracting travelers eager to experience the vibrant culture, stunning landscapes, and delicious cuisine that this charming region has to offer. Visitors during these months can partake in outdoor activities like hiking and cycling along scenic trails or enjoy leisurely strolls through the quaint streets adorned with historic architecture.For those seeking a more tranquil experience, November presents a wonderful opportunity to visit Sant' Ambrogio at a lower cost, while still enjoying the beauty of the area. The autumn foliage creates a captivating backdrop for exploration, and the cooler temperatures in the 50s to low 60s Fahrenheit provide a refreshing atmosphere for sightseeing.Ultimately, deciding when to book a vacation rental in Sant' Ambrogio depends on your preferences for lively summer festivities versus the peaceful charm of the shoulder season.
How early should I book a Sant' Ambrogio vacation rental?
Book your Sant' Ambrogio vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Sant' Ambrogio, Tuscany, Italy?
In Sant' Ambrogio, travelers can immerse themselves in the rich history and stunning landscapes of Tuscany. The area is known for its picturesque countryside and charming medieval architecture, making it a superb base for exploring local attractions. Just a short distance away, visitors can explore the iconic town of Florence, where they can admire masterpieces such as the Duomo and the Uffizi Gallery.Closer to Sant' Ambrogio, the nearby town of Fiesole offers breathtaking views of Florence and is home to ancient Roman ruins and the beautiful Fiesole Cathedral. The lush hills surrounding Sant' Ambrogio are dotted with vineyards and olive groves, providing opportunities for wine tasting and leisurely walks through the scenic landscape.For those interested in art and culture, the nearby town of San Gimignano is famous for its medieval towers and is a UNESCO World Heritage site, showcasing stunning frescoes in its churches.
Can I change or cancel my Sant' Ambrogio home rental booking on Vrbo?
To find Sant' Ambrogio vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.
Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Sant' Ambrogio vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.
If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.
Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.
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