Santee vacation rentals

We found 197 vacation rentals — enter your dates for availability

Discover a selection of 9 homes and other vacation rentals in Santee that are perfect for your trip. Vacation homes offer the best amenities for you and your friends, family, or even pets, such as a hot tub and a washer and dryer. At the end of the day, you'll be sure to find a rental for everyone's needs, including accessible or non-smoking choices.

Vacation rentals with weekly discounts - Santee

Showing deals for:Jan 2 - Jan 9

Image gallery for Lakefront Home at Lake Marion, SC Santee, SC in Wyboo Creek 5 Min to Golf Course

Exterior
9.8 out of 10, Exceptional, (6 reviews)
Exceptional
(6 reviews)

Lakefront Home at Lake Marion, SC Santee, SC in Wyboo Creek 5 Min to Golf Course

Manning, SC

8% off
Price is $277
$1,942 for 7 nights
All fees included
Lakefront Home at Lake Marion, SC Santee, SC in Wyboo Creek 5 Min to Golf Course

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Find out more about Santee

Find out more about Santee

Why visit Santee

  • Outdoor Adventures: Santee is ideal for hiking, fishing, and water sports in its scenic national parks and serene lakes.
  • Romantic Getaways: Couples can enjoy a peaceful retreat with beautiful landscapes and cozy accommodations.
  • Charming Neighborhoods: Explore the friendly atmosphere and unique charm of Santee's local neighborhoods.
  • Vacation Rentals: A variety of accommodation options, including private homes and cabins, cater to all preferences.
  • Nearby Beaches: Enjoy sandy beaches just a short drive away, perfect for relaxation and family outings.

Popular types of accommodation in Santee

If you're planning a getaway to Santee, you’ll find a variety of fantastic vacation rentals to suit your needs. The most popular options include houses, cozy cabins, and charming cottages. Whether you’re looking for house rentals, Santee apartments, or bedroom rentals, we have it all. Plus, many accommodations offer laundry facilities to make your stay even more convenient. Explore Santee's options for an unforgettable vacation experience.

  • Houses: The top choice for travelers in Santee, these homes offer spacious accommodations perfect for families or groups seeking comfort and privacy.
  • Cabins: A favorite for nature enthusiasts, these rustic retreats provide a cozy escape immersed in the beauty of the outdoors.
  • Cottages: These charming abodes are ideal for a quaint and intimate getaway, perfect for couples or solo travelers.
  • Condos: A modern option that combines convenience with comfort, ideal for those wanting easy access to local attractions.
  • Apartments: Great for budget-conscious travelers, these rentals offer a home-like atmosphere with essential amenities.**

Top attractions in and around Santee

Santee, South Carolina, is a perfect destination for outdoor enthusiasts and couples seeking a romantic getaway. With its stunning national parks, serene lakes, and picturesque islands, visitors can enjoy a variety of scenic experiences. Whether you're looking to hike, relax by the water, or explore the natural beauty, Santee offers a delightful mix of attractions that cater to those who appreciate the great outdoors.

  • Santee State Park: Nestled within Santee, this national park offers thrilling outdoor adventures amidst stunning natural scenery. Enjoy hiking, fishing, and camping while immersing yourself in the great outdoors.
  • Santee Indian Mound and Fort Watson Site: Located 4 miles from Santee, this cultural landmark provides a glimpse into the area's rich history, showcasing Native American heritage and the remnants of an early fort.
  • Taw Caw Creek: Just 9 miles away, this picturesque lake features sandy beaches and romantic scenery, perfect for a day of relaxation, picnicking, or enjoying water activities.

Things to do recommended for couples

Discover romance in Santee, South Carolina, with a cozy picnic by Lake Marion or a scenic boat ride at sunset. Explore the lush landscapes together at Santee State Park, and savor a candlelit dinner at a local eatery for an unforgettable evening.

Things to do recommended for families

Your family will love exploring the Santee National Wildlife Refuge, just 4 miles from town, offering serene nature walks and birdwatching. Additionally, Taw Caw Creek Park, located 9 miles away, provides a perfect spot for relaxation and outdoor fun, making it a great day out for everyone.

Things to do recommended for groups

Experience the outdoors with your group at Santee Cooper Country Club and Santee National Golf Club, both offering fantastic golfing opportunities. For a short drive, head to Wyboo Golf Club, about 16 miles away, to enjoy more scenic courses and a great atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation in Santee

When traveling with a group, family, pets, or planning an extended stay, it's important to filter your options based on what matters most to you. Here are some helpful Vrbo booking tips to guide you.

  • Traveling to Santee with a group: Think about how many bedrooms you'll require, along with features like a fully equipped kitchen or outdoor areas for group gatherings. Luckily, you can easily narrow down your options for these and many other preferences on Vrbo.
  • Traveling to Santee with young kids: Traveling with young kids can be quite a challenge. It's important to prioritize their comfort and safety, along with having access to age-appropriate amenities, like a private swimming pool. Additionally, it's wise to think about how close you are to family-friendly attractions.
  • Taking your pets with you to Santee: For many families, a trip isn’t truly fulfilling without their furry companions. If this resonates with you, explore Vrbo listings that welcome pets. Most pet-friendly properties come equipped with feeding bowls and cozy beds, ensuring that every member of the family feels comfortable and at home.
  • Planning for a long term stay visiting Santee: If you're searching for vacation rentals with special offers for stays of a month or more, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include options like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay near Santee

Santee, South Carolina, is a hidden gem perfect for outdoor enthusiasts and romantic getaways. With its scenic beauty and friendly atmosphere, visitors can explore charming neighborhoods and enjoy sandy beaches nearby. Whether you're looking for family-friendly excursions or a peaceful retreat, Santee offers a delightful mix of experiences. Don't miss the opportunity to immerse yourself in the local vibe and discover the area's unique charm during your vacation.

  • Summerton: Summerton is a charming city located 11 miles from Santee, offering a delightful escape for outdoor enthusiasts and romantics alike. The scenic landscapes are perfect for leisurely strolls or picnics, while the nearby recreational areas invite activities like golf. Visitors can enjoy the serene beauty of local lakes and the lush surroundings of national and state parks. Whether you're exploring the tranquil waters or taking in the breathtaking scenery, Summerton promises a perfect backdrop for relaxation and adventure.
  • Vance: Just 5 miles away from Santee, Vance is a hidden gem that beckons travelers with its picturesque outdoor settings and romantic ambiance. The city is surrounded by natural beauty, featuring lakes and an array of recreational areas perfect for golf and leisurely activities. Vance is also close to a national state park and an island, offering opportunities for exploration and relaxation. Enjoy a day spent surrounded by nature or indulge in a round of golf, making Vance an ideal destination for a peaceful getaway.
  • Elloree: Located 6 miles from Santee, Elloree is a wonderful city that captivates visitors with its scenic beauty and outdoor adventures. The area boasts excellent golf courses and recreational spaces, making it a haven for sports enthusiasts. Nature lovers will appreciate the nearby lakes and national parks, where stunning landscapes and diverse wildlife await. With its romantic setting and opportunities for relaxation, Elloree is a fantastic choice for those looking to immerse themselves in the tranquility of South Carolina's countryside.

Best time to go to Santee

If you're planning a trip to Santee, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs in March to April and July, while off-peak times, like October to December tend to have fewer bookings and better deals.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighSlightly Low
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighAverage
May72.0°F (22.2°C)Light RainMostly SunnyAverageAverage
June78.6°F (25.9°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly High
August79.9°F (26.6°C)Light RainMostly SunnyAverageSlightly High
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowAverage
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowAverage

Booking with Vrbo is simple

Are you hoping to save money on your upcoming journey? Being flexible with your travel dates can make a big difference, as prices often fluctuate. Additionally, booking a longer stay can lead to substantial savings. To discover a Vrbo property that suits your budget, feel free to use our filters to narrow down your options by price, location, and type of vacation rental. We're here to help you find the perfect getaway.

Save more with One Key

Reserve an eligible Vrbo for your group getaway and earn OneKeyCash on your entire booking. Being the planner truly has its rewards. By enrolling in our travel rewards program, One Key, you'll gain access to exclusive discounts and earn OneKeyCash on qualifying reservations. Sign up today and start enjoying your savings.

Vrbo Trips: Planning made easy

Vrbo’s Trip Board offers a user-friendly platform for planning your travel adventures. You can easily create new trips, resume your planning from where you left off, or organize your existing plans all in one place. Your saved or booked properties will be neatly organized under categories such as Potential, Upcoming, or Current Trips. To begin exploring Trip Boards, simply visit: https://www.vrbo.com/trips.

**Based on Vrbo properties bookings.

The friendly area of Santee awaits your stay

The lake and surrounding scenery provide a peaceful ambiance to your vacation home in Santee. Travelers to this welcoming city praise the restaurants, golfing and fishing. Whether you're planning a family vacation, friends trip or romantic retreat, Vrbo has a great selection of vacation homes. Many rentals come with a full kitchen and separate dining area, perfect if you need a space for entertaining.

Activities and attractions in Santee

Do you want to discover attractions to visit while you're in the area? Venture out of your cozy vacation rental and experience everything that makes Santee a fun spot to vacation. Here are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Santee Cooper Country Club (0.6 mi / 1 km)
  • Santee National Golf Club (0.8 mi / 1.4 km)
  • Wyboo Golf Club (16.3 mi / 26.3 km)
  • St. George Country Club (22.6 mi / 36.4 km)

Exploring the natural features in Santee

Whether you're looking for adventure or just want to appreciate the scenery, Santee is a great place to spend some time outside. These are some of the area's most enchanting natural features, all within 30 miles (48.2 km) of the city center:

  • Lake Marion (7.9 mi / 12.7 km)
  • Taw Caw Creek (8.5 mi / 13.7 km)
  • Santee National Wildlife Refuge (4.4 mi / 7 km)
  • Taw Caw Creek Park (9 mi / 14.5 km)
  • Goat Island (9.4 mi / 15.1 km)
  • Ferguson Island (12.1 mi / 19.5 km)

Transportation to and around Santee

The nearest airport is in Columbia Metropolitan Airport (CAE), located 49 mi (78.8 km) from the city center.

Frequently asked questions

What is the best area to stay in Santee when booking a vacation rental?
When booking a vacation rental in Santee, South Carolina, one of the best areas to consider is near Lake Marion. This picturesque region offers a range of rental properties, from cozy cabins to spacious lakeside homes, making it a popular choice for families and outdoor enthusiasts. Staying near Lake Marion not only grants you stunning views and easy access to the water, but it also places you close to attractions such as Santee State Park, where you can enjoy hiking, fishing, and picnicking in a serene natural setting.

Another appealing option is the area around the Santee National Wildlife Refuge, which provides a unique opportunity to experience the local wildlife and enjoy beautiful trails.
How much does it cost to rent a vacation home in Santee?
Prices for vacation rentals in Santee vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Santee to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Santee vacation house rentals?
You can find great discounts on house rentals in Santee on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Where are the best areas for renting a beach house in Santee?
For renting a beach house in Santee, South Carolina, travelers should consider the nearby Santee State Park area, which offers a picturesque setting along Lake Marion. This region features a variety of vacation rentals, including lakeside cottages with private docks, spacious porches, and outdoor grilling areas, ideal for families or groups looking to enjoy water activities like fishing and boating.

In addition, the area around the Santee Cooper Resort provides more options, where visitors can find homes that often include amenities such as fully equipped kitchens, cozy living areas, and access to swimming pools or community recreational facilities. This locale is superb for those who appreciate a blend of lakefront relaxation and outdoor adventure.

While Santee itself is not directly on the ocean, it is a short drive from the beautiful beaches of Edisto Island and Folly Beach, making it a convenient base for day trips to the coast. Rentals in these beach towns typically come with features like beach access, outdoor showers, and spacious decks for enjoying the coastal breeze.
What is the most popular type of vacation rental accomodation in Santee?
In Santee, condos are the most popular type of vacation rental, with about 81 available throughout the area. These condos are typically situated near Lake Marion, providing easy access to fishing and boating activities. Travelers can expect amenities such as fully equipped kitchens, spacious living areas, and often private balconies or decks with scenic views of the lake.

Additionally, there are several vacation houses and cottages available, which are superb for families or larger groups. These properties generally feature multiple bedrooms, outdoor spaces for barbecuing or relaxing, and a homey atmosphere that enhances the overall experience.
Are there any family house rentals in Santee?
In Santee, South Carolina, there is a substantial selection of family-friendly homes available, with around 82 options to choose from. This charming area is well-known for its beautiful lakes and outdoor activities, making it an excellent choice for family getaways. Many of these properties come equipped with spacious living areas, full kitchens superb for preparing family meals, and outdoor spaces ideal for children to enjoy.

Visitors can expect amenities such as Wi-Fi, air conditioning, and in some cases, private patios or decks for relaxation after a day of exploration. The nearby Santee State Park offers hiking trails and opportunities for fishing, while Lake Marion is superb for boating and swimming. Families can also discover local dining options and shops within a short drive, enhancing their stay with authentic Southern experiences. See all family-friendly rentals in Santee.
Can I rent a vacation home with a pool or hot tub in Santee?
In Santee, there are plenty of vacation homes available for rent that come with pools and hot tubs, with around 81 options to choose from. This charming town, located near Lake Marion, offers a variety of properties that cater to those looking for a refreshing retreat. Many of these rentals are equipped with private pools, hot tubs, and spacious outdoor areas great for relaxation and gatherings.

Travelers can expect amenities such as fully equipped kitchens, comfortable living spaces, and outdoor dining areas, making it ideal for families and groups. Additionally, some properties may boast scenic views of the lake or surrounding nature, enhancing the overall experience. Find your rental in Santee with a pool or a hot tub.
Can I find long-stay vacation rentals in Santee?
A long-stay vacation rental in Santee is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Are there pet-friendly house rentals in Santee?
In Santee, there are several pet-friendly house rentals available, offering a great opportunity for travelers looking to enjoy the outdoors with their furry companions. Many of these vacation homes are equipped with amenities such as spacious backyards, outdoor seating areas, and fully stocked kitchens, making them ideal for families or groups.

The area is well-known for its proximity to Santee State Park, where visitors can explore nature trails and enjoy activities like fishing and boating on Lake Marion. This scenic park provides a superb backdrop for outdoor adventures with pets, featuring ample open space for walking and playing. Additionally, the lake offers opportunities for swimming and picnicking, making it a fantastic spot for spending quality time with pets and family alike. See all pet-friendly rentals in Santee.
Are there any remote work vacation rentals in Santee?
In Santee, South Carolina, there are numerous vacation rentals that cater to remote work needs, with about 90 options available. These properties typically provide essential amenities such as dedicated workspaces, including desks and ergonomic chairs, as well as high-speed Wi-Fi to facilitate productivity. Many rentals also come equipped with additional features like safes for secure storage, and some may even offer access to business centers for those requiring more extensive facilities.

The area is known for its scenic beauty, particularly around Lake Marion, which provides a peaceful backdrop for work and relaxation. Travelers can enjoy outdoor activities such as fishing or hiking during their downtime. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Santee vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Santee with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Santee?
In Santee, popular vacation rental amenities include kitchens, which allow travelers to prepare their own meals, and shared pools that provide a refreshing way to relax. Many rentals also boast beautiful lake views, enhancing the overall experience of the serene surroundings. Additionally, patios are commonly found, offering outdoor spaces for guests to enjoy the pleasant climate and scenic views.
When is the best time to visit Santee for a vacation rental?
April is the most popular month to visit Santee, South Carolina, as the spring season fully unfolds with pleasant temperatures and vibrant scenery. This period, which spans from March to May, attracts a variety of travelers seeking outdoor adventures, including fishing and golfing, as well as those wanting to enjoy leisurely strolls by the picturesque Santee Cooper Lakes.

During this time, visitors can expect mild weather, typically ranging from the mid-50s to the low 80s Fahrenheit. This climate makes it comfortable for outdoor activities such as birdwatching or exploring the local parks, with opportunities for sightseeing close to the lakes. The allure of spring blossoms and the inclusive setting create a wonderful backdrop for family gatherings or a peaceful retreat.

If you're looking for a more budget-friendly time to visit, consider planning your trip in November. This month offers a quieter experience, allowing for more personal exploration of the area's natural beauty without the crowds.
How early should I book a Santee vacation rental?
Book your Santee vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Santee?
In Santee, visitors can enjoy several attractions centered around the area's natural beauty and recreational opportunities. The Santee State Park is a highlight, offering hiking trails, fishing, and stunning views of Lake Marion, making it a great spot for outdoor enthusiasts. Nearby, the Lake Marion Golf Course provides a scenic golfing experience for those looking to hit the links.

The Santee Cooper Resort area features access to water sports, including boating and kayaking, while the local restaurants offer a taste of Southern cuisine. Additionally, the Santee National Wildlife Refuge, located a short drive away, is superb for birdwatching and exploring the diverse ecosystems of the region.
Can I change or cancel my Santee home rental booking on Vrbo?
To find Santee vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy flat or a countryside retreat, you can turn your space into a standout destination—become a host and let Vrbo handle the heavy lifting to help you thrive.
Are all fees included in the Santee vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.

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