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Santee houses
We found 1,072 houses — enter your dates for availability
Explore Santee house rentals
6BR Resort-Style Pool, Mini Golf & Firepit Retreat
Sleeps 16 · 6 bedrooms · 3 bathrooms
9.49.4 out of 10
Exceptionalexceptional
23 reviews(23 reviews)
Hiker’s Paradise! Heated Pool, fire pits, and views
Sleeps 10 · 3 bedrooms · 2 bathrooms
1010 out of 10
Exceptionalexceptional
2 reviews(2 reviews)
Resort Style Home
Sleeps 16 · 5 bedrooms · 3 bathrooms
1010 out of 10
Exceptionalexceptional
2 reviews(2 reviews)
Santee! Non-stop fun! Relax, Recharge, Rejoice! California here we come!
Sleeps 4 · 1 bedroom · 1 bathroom
Santee Home Away From Home-Next to parks & trails!
Sleeps 8 · 4 bedrooms · 2 bathrooms
8.08.0 out of 10
Very goodvery good
4 reviews(4 reviews)
Newly remodeled 1 story house with big backyard, near highway 52
Sleeps 4 · 2 bedrooms · 1 bathroom
Top rated house rentals - Santee
Pleasant stay!
1010 out of 10
Exceptionalexceptional
38 reviews(38 reviews)
Spacious home in a great location
1010 out of 10
Exceptionalexceptional
115 reviews(115 reviews)
Spacious San Diego House
1010 out of 10
Exceptionalexceptional
13 reviews(13 reviews)
Fantastic
1010 out of 10
Exceptionalexceptional
106 reviews(106 reviews)
San Diego Stay
1010 out of 10
Exceptionalexceptional
45 reviews(45 reviews)
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- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
Are there any vacation home rentals in Santee?
Choose one of our 1,072 vacation home rentals in Santee and you’ll have the ideal base for your next trip. Carlton Hills, Fletcher Hills and Lake Murray are some of the city’s most sought-after neighborhoods.
How much does it cost to stay in a vacation rental house in Santee?
A range of factors will determine the price of a vacation home rental in Santee, such as property size and how long and when you plan to stay. All you have to do is key in your travel dates and preferences to find a house that meets your budget and taste.
When is the best time to rent a vacation house in Santee?
The best time is whenever you can break free from your daily routine and enjoy the weather you like most. For most people searching for a vacation home rental in Santee, East County, that’s March. Average daily temperatures during this month range from 9ºC (48ºF) to 20ºC (68ºF).
Where can I rent a Santee vacation house with great views?
There’s only one thing better than spending your time away in one of our Santee vacation home rentals — staying someplace that comes with awesome views. Scroll through our options to discover a house with the amenities you need and the vistas that’ll make your trip even more special. Sort your results by “Recommended” or “Guest rating” and see what’s available.
Does Santee have any weekend house rentals?
Browse our weekend rentals and get ready for a thrilling few days away. Our main tips for booking your perfect house in Santee? Stay flexible when searching and adjust your travel dates until you find the vacation home rental that matches your style.
Are there any pet-friendly house rentals in Santee?
With our filter tool, finding a pet-friendly vacation home rental in Santee is easy. Simply click on “Pets allowed” to look for houses that come with extras to make your four-legged friend feel welcome, such as pet toys and plenty of outdoor space.
What are the top things to do in Santee?
Planning a memorable trip to Santee means discovering cool things that the family will love. Balboa Park, Snapdragon Stadium and Fashion Valley Mall are just the start of the options here. And Vrbo’s vacation home rentals are the ideal base for your sightseeing activities.
Why should I book my vacation rental house with Vrbo?
When you select a Vrbo vacation home rental, the only people you’ll share your space with are the people you take with you. It will only be you, the family and the whole property to yourselves. Our flexible cancellation policies also mean you can book your rental house with confidence if you need to change your plans.