Caloosahatchee Vacation Rentals, FL, USA: house rentals & more

Select from 1019 houses, 53 apartments, and other vacation rentals to find the perfect place for your stay in Caloosahatchee. Whether you’re staying in a vacation home with a group or just with your pet, you'll have the best amenities for spending time at your home away from home, which might include WiFi and a washer and dryer. Whatever you're looking for, you'll find a rental that has what everyone needs, including a place that's non-smoking or offers accessibility.

Find spaces that suit your style

House

Condo/Apartment

Find the best place to stay - Caloosahatchee

New listing - Villa Orchid 3bds/2 baths heated pool in Cape Coral

Sleeps 8 · 3 bedrooms · 2 bathrooms

Brand New Remodel! - River View! - Tiki Hut on the Water! - Southern Exposure!

Sleeps 10 · 4 bedrooms · 2 bathrooms

Waterfront Retreat.Kid&Pet friendly! Relax & Fish off dock.Now booking 2026

Sleeps 6 · 3 bedrooms · 2 bathrooms

Casa Del Rio, Tropical Resort Feel, Breathtaking River Views, Large Pool & Dock

Sleeps 6 · 3 bedrooms · 2 bathrooms

Top rated rentals - Caloosahatchee

Home sweet home

Peace of mind
Our Book with Confidence guarantee gives you 24/7 support
More quality time
From booking to staying, the whole process is simple and enjoyable
All the privacy of home
Enjoy full kitchens, laundry, pools, yards and more
More for less
More space, more privacy, more amenities — more value

Frequently asked questions

What is the most popular type of vacation rental accommodation in Caloosahatchee?

According to our data, houses are the most desirable vacation property type in Caloosahatchee. But naturally, everyone’s idea of an awesome stay isn’t going to be the same. Vrbo has vacation rentals of all shapes and sizes, and we’ll help you to find your ideal fit.

How much does it cost to rent a vacation rental in Caloosahatchee?

The average price for a vacation rental in Caloosahatchee is determined by a number of factors, such as season, length of stay and property type. Whether you’re dreaming about a sprawling villa with a pool or a comfy cabin perfect for just you and the kids, just enter your dates of travel to find stays with exceptional value.

How much does it cost to rent a beach house in Caloosahatchee?

When you travel and the style and size of the property will influence the cost of your beachside vacation rental. Put in your Caloosahatchee travel dates to view your available options on Vrbo. Did someone just say “hot tub”? Use the filters to select the amenities and features you want in your vacation home.

Are there large group vacation rentals in Caloosahatchee?

Caloosahatchee has 75 vacation properties that can accommodate 10 or more guests. These properties come with the privacy and space you need to share good times with loved ones.

Can I find two-bedroom vacation rentals in Caloosahatchee?

Caloosahatchee has 121 two-bedroom vacation rentals that you can choose from. Enjoy a vacation home with all the space and privacy you need at a price that’s hard to resist on Vrbo.

Are there vacation rentals with WiFi in Caloosahatchee?

Whether you want to stay in touch with world events, write a few emails or surf social networks, there are 393 vacation homes with WiFi in Caloosahatchee. Check the “WiFi” box when searching on Vrbo and stay connected on your vacation.

How old do you have to be to rent a vacation rental in Caloosahatchee?

It’s advisable to check with the Caloosahatchee vacation property you’re looking at on Vrbo as age restrictions differ. However, generally it’s 16, 18 or 21.

How long can I rent a vacation rental in Caloosahatchee for?

How long you can book a vacation rental in Caloosahatchee is down to the property. Just enter your desired travel dates to view a list of options offering extended stays. With loads of creature comforts such as kitchens and air conditioning, as well as some offering weekly or monthly discounted prices, you’re sure to get a perfect place to call your home away from home in Caloosahatchee.