Isle of Palms houses

Pick one of our 968 holiday home rentals in Isle of Palms and you’ll have a perfect base for your next trip. Yacht Harbour Court, Seaside Farms and Sandcrab are some of the city’s most sought-after neighbourhoods.

Where you stay, when you want to travel and your trip length will determine how much you pay for a holiday home rental in Isle of Palms. Key in your travel details on Vrbo to compare properties and then choose the right one for you.

Vrbo makes it easy to book your holiday home rental in Isle of Palms whenever you decide to go. Start by considering the weather conditions for the month you’re thinking of visiting. Going in the high season? Book early to get the best availability.

Vrbo has some awesome holiday home rentals in Isle of Palms, including houses with beach views. Before and after seeing the sights, chill out and stare at scenes that are their own attraction.

Some of our holiday houses can be rented just for the weekend, making them ideal for spontaneous getaways. Enter your desired travel dates to view the availability. You may need to switch up the dates and be flexible with your plans to find the right holiday home rental in Isle of Palms.

There are 21 holiday home rentals that allow pets in Isle of Palms, so your furry friend won’t miss out on the excitement! Use our filter tool to look for pet-friendly houses that come with perks like dogs beds and free treats for them, and a bunch of cosy conveniences for you.

It’s no surprise why many families love Isle of Palms, with cool attractions like USS Yorktown, Charleston City Market and Waterfront Park to explore. Check out this destination’s wonders together and then return to the comforts of your holiday home rental.

Booking a holiday home rental with Vrbo means you get the entire place for your exclusive use — your own private space, with no interruptions or distractions from anyone else. Also, our easy payment and cancellation policies give you the freedom to modify your plans if required. Plus, our One Key™ rewards programme lets you earn OneKeyCash™* on all eligible bookings on Vrbo. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo.