Syracuse villas

Browse our 682 villa rentals in Syracuse that are often set in beautiful and exclusive locations. Whether you want to stay in Ortigia, Santa Lucia, Acradina or another well-known neighbourhood, you’ll discover the ideal villa on Vrbo.

Prices vary depending on length of stay, time of year and exact location, so enter your trip details to discover what’s available. Whatever your style or budget, Vrbo has villa rentals in Syracuse for guests of every type.

The best time to visit Syracuse depends on things like activities that you want to try and your favourite season. With average temperatures ranging between 17ºC (63ºF) and 20ºC (68ºF), May is a popular month to get a villa rental in this part of Province of Syracuse. Want to really experience the community and culture of this destination? Check for major events or festivals and arrange your villa rental around them.

Villa rentals with views of historic areas are just one of the types of stays you can book in Syracuse. If you’re looking for spacious villas that offer vistas worth remembering, you’ll discover them on Vrbo.

Equipped with a host of amenities like swimming pools, beautiful courtyards and advanced in-home entertainment, Vrbo’s luxurious villa rentals in Syracuse promise a deluxe travel experience. Look forward to enjoying the very best in modern and comfortable furnishings, plenty of room and a setting that ensures privacy and tranquility for you and your guests.

One of the first things to do after booking your villa rental is to pack your itinerary with enjoyable activities. There’s plenty of them in Syracuse, with top-rated family-friendly attractions including Cathedral of Syracuse, Temple of Apollo and Museo Archeologico Regionale Paolo Orsi.

Book your villa rental with Vrbo and experience more privacy and space compared to traditional hotel accommodation. These kinds of stays offer that home-away-from-home ambience. One of the best benefits? You’ll never have to share your space, whether you spend your getaway in a villa or something a little swankier, like an estate or a castle. And if you’re a member of our One Key™ rewards programme, you can collect and redeem OneKeyCash™* on eligible bookings on Vrbo. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo.