Photo by Isabelle Bhend

Santa Fe de Antioquia vacation rentals

We found 83 vacation rentals — enter your dates for availability

Discover a selection of 5 homes and other vacation rentals in Santa Fe de Antioquia that are perfect for your trip. Whether you’re staying in a vacation home with your kids and pets or just with friends, you'll have the amenities you expect and more, which might include WiFi and a washer and dryer. Whatever you're looking for, you'll be able to choose a rental to meet everyone's needs, including accessible or non-smoking choices.

Find spaces that suit your style

  • Peace of mind
    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time
    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home
    Enjoy full kitchens, laundry, pools, yards and more
  • More for less
    More space, more privacy, more amenities — more value

Why people love visiting historic Santa Fe de Antioquia

Enjoy the area's history, monuments and cathedral and make a vacation rental your home during your stay in Santa Fe de Antioquia. Well known for its festivals, riverfront and art, this relaxing city won't disappoint. Many of our vacation rentals offer full kitchens, spacious living quarters, and sometimes even a hot tub for a relaxing getaway.

Exploring the natural landscape of Santa Fe de Antioquia

Whether you're looking for fun outdoor activities or just want to take in the scenery, you'll be sure to find the perfect setting for your vacation in Santa Fe de Antioquia. Here are some of the area’s most enchanting sights, all within 30 miles (48.2 km) of the city center:

  • El Gaitero Ecopark (9.3 mi / 15 km)
  • San Jeronimo Park (10.4 mi / 16.8 km)
  • Principal Park (26.8 mi / 43.1 km)

Frequently asked questions

What is the best area to stay in Santa Fe de Antioquia when booking a vacation rental?
Among the more popular locations to experience a vacation home in Santa Fe de Antioquia is Zona Colonial. Spend your break here and you’ll be near some top visitor attractions including Iglesia de Santa Bárbara and Cathedral of Santa Fe de Antioquia.
What is the most popular type of vacation rental accommodation in Santa Fe de Antioquia?
The most popular types of vacation rentals in Santa Fe de Antioquia are villas. Searching for something different? Vrbo has many options to match our guests’ needs, so you’ll see vacation properties in lots of shapes and sizes. The perfect fit is ready and waiting for you — get hold of yours today.
How much does it cost to rent a vacation rental in Santa Fe de Antioquia?
Different factors determine the price of a vacation rental in Santa Fe de Antioquia, including the time of year, property type and length of stay. However, all our vacation homes have something in common — unbeatable value. Just enter your travel dates to find your ideal match.
How much does it cost to rent a beach house in Santa Fe de Antioquia?
The average price for a vacation rental close to the beach in Santa Fe de Antioquia depends on when you’ll be there and the style and size of property you’re looking for. Find prices easily on Vrbo by entering your travel dates. Then use the handy filter tool to choose the number of bedrooms and amenities that you prefer, such as WiFi, a pool and air conditioning.
Are there pet-friendly vacation rentals in Santa Fe de Antioquia?
There certainly are. Pick from three vacation homes that roll out the welcome mat in Santa Fe de Antioquia on Vrbo. Our cuddly best friends deserve a break too, so simply use our search function for pet-friendly vacation rentals to find a property where your pooch can be near his favorite humans.
Can I rent a house with a pool in Santa Fe de Antioquia?
Pack your swimwear and inflatable swan, because there are two houses with a private pool in Santa Fe de Antioquia. Book one of these superb vacation rentals and every day will be a pool day. Simply enter your travel dates into Vrbo, then use the “pool” filter to find the ideal place for a splashing good time!
What are popular rental amenities in Santa Fe de Antioquia?
A barbecue grill, a swimming pool and a garden top the list of most popular rental amenities in Santa Fe de Antioquia. Whether you’re heading away alone, with your other half or a group of friends, Vrbo will help you find a vacation home that matches your style with a load of extras you’ll love.
Are there large group vacation rentals in Santa Fe de Antioquia?
Take your pick of three Vrbo vacation homes in Santa Fe de Antioquia that can sleep five or more people. You’ll get all the space and privacy you need to have fun with your nearest and dearest — and nobody else.
Are there vacation rentals in Santa Fe de Antioquia that welcome kids?
Santa Fe de Antioquia has three family-friendly vacation homes to choose from. And finding a stay that welcomes youngsters is a breeze with Vrbo’s “Properties good for families” filter. In addition to having the whole place to yourselves, you’ll also enjoy access to conveniences and perks such as extra bedrooms, private pools and yards.
What are the top attractions for families in Santa Fe de Antioquia?
There are lots of fun things to do and see with the family in Santa Fe de Antioquia, including:

  • Museo Juan del Corral
  • Bridge of the West
  • Iglesia de Santa Bárbara

Can I find two-bedroom vacation rentals in Santa Fe de Antioquia?
Take off with your besties and enjoy peace, privacy and comfort in one of the two two-bedroom vacation homes Santa Fe de Antioquia has to offer.
How can I find vacation rentals with air conditioning in Santa Fe de Antioquia?
Santa Fe de Antioquia has two vacation rentals where you’ll be able to spend your days in air-conditioned comfort. To book a stay on Vrbo offering this perk, enter your desired travel dates and use the filter tool to select the “air conditioning” box.
How old do you have to be to rent a vacation rental in Santa Fe de Antioquia?
The minimum required age is normally 16, 18 or 21. It can differ between properties on Vrbo, so look at the rules of your chosen Santa Fe de Antioquia stay before booking your escape.
How long can I rent a vacation rental in Santa Fe de Antioquia for?
The length of time you can book a vacation rental in Santa Fe de Antioquia differs according to the property. Just enter your chosen dates to view a list of options offering extended stays. With a range of features like washing machines and air conditioning, as well as some offering weekly or monthly discounted prices, you’re sure to find somewhere perfect to call your home away from home in Santa Fe de Antioquia.

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