La Mesa houses

Select one of our 3,062 holiday home rentals in La Mesa and you’ll have the perfect base for your next travel adventure. Windsor Hills, Rolando Village and Grossmont are some of the city’s best areas to stay.

Your picture-perfect holiday home rental in La Mesa awaits on Vrbo, with a range of prices from wallet-friendly accommodation to more exclusive properties. Enter your trip details to filter your search, making sure you find the best place that everyone will love.

It can all depend on the type of weather you enjoy, among other factors. Many people visiting East County book a La Mesa holiday home rental in May, when the average temperature ranges from 13ºC (55ºF) to 22ºC (72ºF).

Vrbo makes it easy to find the stunning views you’re looking for in your holiday house. Just use our “Location” filter to narrow down the kind of area you’d prefer to stay in, and the views you want to stare out at, while searching holiday home rentals in La Mesa.

Explore our weekend rentals and get packing for a thrilling couple of days away. Our tips for booking your ideal house in La Mesa? Be flexible when searching and change your dates until you find the holiday home rental that matches your needs.

Spend your next adventure with your furry friend at one of our five pet-friendly holiday home rentals in La Mesa. These stays come with perks that’ll make your pup feel welcome, including a backyard to play in. Just select the “Pets allowed” filter to book a house that has room for every beloved member of your family.

It’s easy to see why families love La Mesa, with cool attractions like San Diego Zoo, Balboa Park and Petco Park to explore. Discover this destination’s wonders together and then return to the cosy comforts of your holiday home rental.

Vrbo takes the stress out of finding your dream holiday home rental. Use our filters to fine-tune your search by property type, nightly price, location and more. Whatever your preference, you’ll always get the entire property for you and whoever you’re travelling with. Also, our cancellation policies offer peace of mind should your plans change. You’ll get your money back if you cancel your booking within the timeframe specified by the property’s cancellation policy. What’s more, our free rewards programme, One Key™, lets you earn and spend OneKeyCash™* on eligible bookings on Vrbo. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo.