Big Pine Key houses
We found 627 houses — enter your dates for availability
Explore Big Pine Key house rentals
Keys 3 Bedroom Corner Home near Beach & Key West
Sleeps 10 · 3 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
5 reviews(5 reviews)
Old Wooden Bridge Resort and Marina
Sleeps 6 · 2 bedrooms
8.68.6 out of 10
Excellentexcellent
217 reviews(217 reviews)
Big Pine Key! 3 bedroom house 2 bath sleeps 6
Sleeps 6 · 3 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
8 reviews(8 reviews)
Tropical Caribbean Paradise with pool!
Sleeps 4 · 1 bedroom
9.29.2 out of 10
Wonderfulwonderful
85 reviews(85 reviews)
Oceanfront Paradise w Dock for your 35' boat and Huge Tiki and Firepit. Dogs OK
Sleeps 6 · 3 bedrooms · 2 bathrooms
9.89.8 out of 10
Exceptionalexceptional
16 reviews(16 reviews)
Big Pine Key, 3 BR, 2 1/2 Bath, Private Canal, Close to everything, KW
Sleeps 6 · 3 bedrooms · 2+ bathrooms
8.68.6 out of 10
Excellentexcellent
12 reviews(12 reviews)
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Frequently asked questions
Are there any vacation home rentals in Big Pine Key?
Opt for one of our 627 vacation home rentals in Big Pine Key and you’ll have the perfect base for your next great adventure. Sands, Whispering Pines and Atlantis Estates are among the city’s most sought-after neighborhoods.
How much does it cost to stay in a vacation rental house in Big Pine Key?
Whether you’re searching for a budget-conscious getaway or an upscale retreat, Vrbo has a range of vacation home rentals in Big Pine Key to choose from. Use our filter tools to narrow down your options and find the perfect stay that meets your needs.
Where can I rent a Big Pine Key vacation house with great views?
Use the “Location” filter to find a vacation home rental with the views you’re looking for. Start by entering the dates you want to book your house in Big Pine Key, then narrow your options based on the type of area you’d rather stay in.
Does Big Pine Key have any weekend house rentals?
Some of Vrbo’s vacation houses can be rented just for the weekend, making them perfect for impulsive getaways. Key in your desired travel dates to view the availability. You may need to adjust the dates and be flexible with your travel plans to find the right vacation home rental in Big Pine Key.
Are there any pet-friendly house rentals in Big Pine Key?
You bet. There are 17 vacation home rentals where pets are allowed in Big Pine Key, so your furry companion doesn’t have to miss out on the adventures. Use our filter tool to search for pet-friendly houses that feature perks like dog beds and complimentary treats for them, and plenty of cozy conveniences for you.
What are the top things to do in Big Pine Key?
From Bahia Honda State Park to Calusa Beach and National Key Deer Refuge Visitor Center, there are plenty of exciting things to do and see during your family escape to Big Pine Key. With the sightseeing sorted out, we’re here to help you find a vacation home rental that fits your taste and budget.
Why should I book my vacation rental house with Vrbo?
Vrbo takes the hassle out of finding your ideal vacation home rental. Use our filters to fine-tune your search by nightly price, property type, amenities and more. Whatever your preference, you’ll always get the entire property for you and whoever you’re vacationing with. Plus, our cancellation policies offer peace of mind should your plans change. You’ll get a complete refund if you cancel your booking within the timeframe specified by the property’s cancellation policy.