East Syracuse house rentals

Discover a range of vacation home rentals in East Syracuse, where there’s a price to match every preference. From economical picks to upscale properties, we make it a cinch to compare options and find the best stay for your next adventure.

August is when most Vrbo guests stay in a vacation home rental in East Syracuse, which is in Town of De Witt. On average, temperatures range from 57ºF (14ºC) to 77ºF (25ºC) at this time of year.

If your idea of a relaxing getaway is one enjoying glorious vistas without leaving the property, we’ll help you book a vacation home rental you’ll love. Into views of historic areas? Vrbo has houses in East Syracuse that feature just that.

Explore our weekend rentals and get ready for a thrilling few days away. Our main tips for booking your perfect house in East Syracuse? Stay flexible when searching and change your travel dates until you find the vacation home rental that fits your style.

If you’d love to experience East Syracuse with your four-legged bestie at your side, use our filter tool to search for pet-friendly houses. Select “Pets allowed” to find a vacation home rental with perks like dog bedding and complimentary treats. After all, when the family goes away, the pets should tag along too!

Planning a memorable getaway to East Syracuse means finding exciting things for all the family. Museum of Science and Technology, Carrier Dome and Rosamond Gifford Zoo are just two of the many options here. And our vacation home rentals are a terrific base for your sightseeing activities.

When you opt for a Vrbo vacation home rental, the only people you’ll share your space with are the people you bring with you. It’ll only be you, your family and the entire place for your exclusive use. Plus, when you sign up to our One Key™ rewards program, you can earn and spend OneKeyCash™* on eligible bookings on Vrbo, Expedia and Hotels.com. Also, our flexible cancellation policies also mean you can book your rental house with confidence if you have to change your plans. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.