Vacation rentals near Edisto Island Museum
We found 2,501 vacation rentals — enter your dates for availability
If you want to to stay within easy reach of Edisto Island Museum, take a look at vacation rentals to choose your home away from home. Whether you’re staying in a vacation home with your kids or with friends, you'll find the best amenities for hanging out with the people that matter most, such as WiFi and cable TV. Whatever you're looking for, you'll be able to choose a rental that has what everyone needs, including a place that is accessible or non-smoking.
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Find the best place to stay - Edisto Island Museum
2025 VRBO Vacation Rental of the Year! Pool, Hot Tub & Deep Water Dock
Sleeps 12 · 5 bedrooms · 4+ bathrooms
10 out of 10
exceptional
(14 reviews)
Top rated rentals - Edisto Island Museum
ladies beach retreat
10 out of 10
exceptional
(143 reviews)
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
More quality timeFrom booking to staying, the whole process is simple and enjoyable
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value